The introduction of Artificial Intelligence (AI) in healthcare is profoundly affecting every aspect of the industry, from clinical care to administration, promising a future where patient care is of higher quality, more efficient, and more personalized. This transformation, while promising, also necessitates thoughtful workflow reengineering as well as human oversight to maximize benefits and mitigate risks. The first part of this chapter presents the basic concepts of AI and how AI-based technologies have been applied in healthcare. The second part provides a comprehensive look at how such technologies are reshaping clinical workflows, offering insights into the benefits, challenges, and future directions of this transformation.