This study investigates the impact of scanning strategies (stripe, meander, and chessboard) on the wear behavior of Co-Cr-Mo alloy fabricated using direct metal laser sintering (DMLS). Ball-on-disc wear tests were conducted to evaluate the effects of different scanning strategies on wear behavior. Tests were performed at three loads (10 N, 15 N, and 20 N) for samples printed with each scanning strategy, and the wear tracks were examined using optical microscopy to determine width and depth. The obtained results indicate significant variations in wear rate and coefficient of friction. Samples built with the meander scanning strategy exhibit superior wear performance compared to those built with stripe and chessboard strategies across all loads. Notably, samples fabricated with the chessboard scanning strategy at a 20 N load exhibit the highest wear rate of 1.0429 × 10–7 mm3/N·m. These findings have implications for optimizing scanning strategy for enhanced wear resistance in DMLS printed metallic parts. This study provides valuable insights for industries reliant on bio-metallic and aerospace components, offering guidance for additive manufacturing processes aimed at producing wear-resistant parts.