This chapter reviews the methods and application of artificial intelligence (AI) in lifestyle medicine research. The chapter highlights how AI technologies have been used to develop individualized interventions via accurate pattern recognition and classification using machine learning and neural networks. The integration of AI in lifestyle and nutritional medicine is examined, showcasing its applications in predicting chronic disease risks, optimizing dietary recommendations, and improving health outcomes. Ethical considerations, challenges, and future directions for AI in lifestyle medicine are also discussed, emphasizing the need for interdisciplinary collaboration and responsible implementation.