Wear and reduction of blowers’ efficiency with moving working bodies makes it suitable to use jet devices in many technological processes. Using swirling flow properties, such as pressure reduction on the axis, created vortex ejectors, but their energy performance and efficiency were reduced. So, they required further optimization of geometrical parameters and study of flow in them. This paper aims to optimize the geometrical dimensions of the vortex chamber and supply channels to improve the energy performance of a homogeneous medium vortex chamber ejector based on design experiment methods. After experimental studies and verification of the mathematical model, the planning of the numerical experiment was carried out, the factors and the target function (ejector efficiency) were selected, and the regression equation was obtained, which allowed to determine the maximum efficiency and the geometrical parameters of the ejector corresponding to it. The numerical experiment was carried out based on solving the equations of fluid motion using the OpenFoam software. In contrast to the vortex chamber ejector with a drainage channel, it was determined that the height of the vortex chamber has a significant effect on the ejector efficiency and should be minimized. Along with linear effects, interaction effects were also significant. To increase efficiency, it is necessary to strive to decrease vortex chamber height and supply tangential channel diameter by decreasing the diameter of the vortex chamber.