The 5-Step Method is a psychosocial intervention that aims to support those affected by another’s alcohol, other drug or gambling behaviour in their own right. It is a unique intervention for several reasons, including its theoretical underpinnings and focus on affected family members (AFMs) in their own right, its commitment to being evidence-based and its global reach, which balances the need to retain implementation fidelity while offering a culturally appropriate and person-centred response to an immense global public health issue. This chapter summarises the key elements of a programme of work that spans over five decades, including pre- and post-Family Member Questionnaire data from more than 850 AFMs that illustrate how a brief, structured intervention can reduce symptoms of ill-health and overall family burden, facilitate changes in coping and improve support. The chapter ends with some reflections on the successes and ongoing challenges for work that must constantly battle against policy reluctance to give the plight of AFMs the recognition and support they need.