Mohs surgeryMohs surgery can have profound psychological impact on patients. Considered the treatmentTreatment of choice for the excision of cosmetically sensitive, treatmentTreatment-resistant cutaneousCutaneous tumors, Mohs surgeryMohs surgery offers many benefits. For a majority of patients, Mohs surgeryMohs surgery provides excellent cosmetic outcomes and a feeling of relief that their cancer has been eradicated. Patients may even demonstrate improvements in quality of life and sun-protectionSun protection behavior. However, for some patients, Mohs surgeryMohs surgery can cause serious psychological problems because of the disfigurementDisfigurement that has resulted from surgery. DisfigurementDisfigurement, especially that of the face, can have detrimental effects on a patient’s psyche. Patients with disfigurementDisfigurement suffer from negative self-image and are often confronted with stigmatization in social interactions. Consequently, patients with disfigurementDisfigurement may develop secondary psychiatric disorders, including social phobiaSocial anxiety disorder/social phobia, generalized anxiety, and/or depressionDepression. Understanding how to best diagnose and manage patients with such psychiatric sequelae is an extremely important aspect of patient care in dermatological surgery practice.