Skin graftsSkin graft are useful when primary closures or flapsFlap are not feasible because of the size or location of the wound. A defining characteristic of grafts is that they are completely separated from the original blood supply and depend on the development of a blood supply with the recipient wound bed. Full-thickness skin graftsSkin graft (FTSGs), split-thickness skin graftsSkin graft (STSGs), and composite grafts (CGs) are three broad categories of skin graftsSkin graft. The choice between grafts depends on the recipient site wound condition, thickness, size, and cosmetic concerns. While grafts do not have quite the cosmetic match as flapsFlap, harvesting from anatomic locations that are similar in color and texture to the wound is beneficial. Appropriate patient selection, meticulous execution, and close follow-up are essential to ensure successful grafting. Both the cosmetic and functional outcomes can be excellent. Additionally, there are several skin substitutes available that can be used as adjuncts in the management of acute and chronic wounds, each with their own advantages and disadvantages.