In this work we studied the device performance of a piezoelectric nanogenerator based on a green, lead-free BZT-BCT thin film. This research interest is situated within the broader framework of the internet of Things (IoT) addressing the challenge of the development of self-powered devices which has sparked significant attention. The implementation of nanogenerator, such as Piezoelectric Nanogenerators (PENGs), is a prominent focus also in the biomedical field regarding implantable devices which must be constructed with non-toxic materials. To this end, we choose to study the possibility to implement a PENG based on lead-free material such as perovskitic Barium Zirconate Titanate- Barium Calcium Titanate commonly known as BZT-BCT whose ferroelectric and piezoelectric properties have been fully characterized in a previous experimental work. In this simulation work, we studied the device performance by means of an equivalent electromechanical model integrated in a more complex circuit. The equivalent circuit has been simulated using LTSPICE software. The results demonstrate that the produced output power is a function of the load. A parametric analysis has been carried out by changing the value of the load from 1 kΩ to 100 kΩ and by imposing a Force of 1.4 mN. The maximum obtained value of the produced power dependent on the load and is equal to 19 μW in the case of 100 kΩ. The results obtained by LTSPICE validated the use of a such material as a possible candidate for energy harvesting devices.