Estimating the final ischemic lesions is important for guiding treatment decisions in stroke patients. The baseline infarct and penumbra are two of the most important pre-interventional biomarkers for prognosticating stroke patients. Baseline CT scans implicitly contain information about these biomarkers. This study evaluates the added value of including NCCT/CTA-based baseline lesion masks as input to predict the final infarct. Given that CTP scans are less accessible than other CT modalities, particularly in medically underserved areas, we analyze two scenarios: when baseline CTP scans are available and when they are not. Using the nnU-Net framework, we observe a 16% improvement in Dice when baseline lesion masks are added in the absence of CTP. However, when CTP maps are included, the addition of baseline lesion masks is no longer beneficial.

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Utilizing Baseline Infarct and Penumbra Masks to Improve NCCT and CTA Based Final Infarct Prediction

  • Mahsa Mojtahedi,
  • Laura van Poppel,
  • Lucas de Vries,
  • Bart Emmer,
  • Charles Majoie,
  • Henk Marquering

摘要

Estimating the final ischemic lesions is important for guiding treatment decisions in stroke patients. The baseline infarct and penumbra are two of the most important pre-interventional biomarkers for prognosticating stroke patients. Baseline CT scans implicitly contain information about these biomarkers. This study evaluates the added value of including NCCT/CTA-based baseline lesion masks as input to predict the final infarct. Given that CTP scans are less accessible than other CT modalities, particularly in medically underserved areas, we analyze two scenarios: when baseline CTP scans are available and when they are not. Using the nnU-Net framework, we observe a 16% improvement in Dice when baseline lesion masks are added in the absence of CTP. However, when CTP maps are included, the addition of baseline lesion masks is no longer beneficial.