Indonesia territory is a naturally disaster-prone region. Due to Indonesia’s high level of social diversity, losses from natural hazards vary considerably. However, the extent to which social vulnerability and risk to natural hazards have been discussed in Indonesia has been limited. Furthermore, there are few studies that analyze the resulting index’s uncertainty. As a result, it is critical to conduct a nationwide assessment of social vulnerability and delineation of natural risk. The Social Vulnerability Index (SoVI) was used to quantify social vulnerability in this study. This study employs 30 variables, which are standardized then reduced to seven factor using factor analysis which explain 72.064% of the variance. Socioeconomic status, population density, age and family structure, female population and special needs, villages with inadequate infrastructure, health insurance, and medical services are the seven factors. The SoVI scores were mapped using a standard deviation classification. Eastern Indonesia, as well as the Nias and Mentawai Island, have areas with high level of social vulnerability. The index that has been developed is sufficiently robust to be used in Indonesia to assess social vulnerability. Delineating risk zones was formed by integrating the map of SoVI with the susceptibility maps. The results indicate that the majority of Indonesia is at moderate to high risk of natural hazards. The results of the social vulnerability and delineation of natural risk assessment can be used to compare social vulnerability and delineation across Indonesian regions and to inform the formulation of policies aimed at reducing social vulnerability and the risk of natural hazards.