Our study presents a comparative analysis of compression of three specimen groups, each in distinct microstructureMicrostructure conditions of the ZnAlAg alloyZnAlAg alloy. These groups are subjected to staggered loads to homogenize and refine the grain size. The X-ray diffraction technique identifies the crystalline phases α, η, and the intermetallic ε, and shows their position and evolution according to the applied load. The micro-hardnessHardness test, conducted in the plastic and packing zone under the ASTM E384 standard, further supports our findings. We have established a statistical relationship between the evolution in the diffraction peaks, micro-hardnessHardness, and applied load. Our research suggests practical implications for the heat treatment and deformation process of the Zn22Al4Ag alloy, allowing for more plasticity due to grain refinementGrain refinement, improved distribution of the intermetallic ε, and the absence of work hardening, leading to a softening or a negative slope of the Hall–PetchHall-Petch model.