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Median arcuate ligament syndrome (MALS) is a rare condition characterized by the compression of the celiac artery and celiac plexus by the median arcuate ligament. This chapter examines the diverse symptoms associated with MALS, such as postprandial epigastric pain, nausea, weight loss, and exercise intolerance, and addresses the diagnostic challenges posed by its overlapping presentation with other gastrointestinal and psychiatric disorders. The discussion emphasizes the importance of distinguishing MALS from other similar conditions, advocating for a thorough differential diagnosis process. A multidisciplinary approach to diagnosis and management is highlighted as essential for optimizing patient outcomes.

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Symptoms, Presentation, and Differential Diagnosis of Median Arcuate Ligament Syndrome

  • 章节

  • 发表日期：

    2025年

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  • Leif Sorensen,
  • Jennifer Curti,
  • Nathan G. Richards

摘要

Median arcuate ligament syndrome (MALS) is a rare condition characterized by the compression of the celiac artery and celiac plexus by the median arcuate ligament. This chapter examines the diverse symptoms associated with MALS, such as postprandial epigastric pain, nausea, weight loss, and exercise intolerance, and addresses the diagnostic challenges posed by its overlapping presentation with other gastrointestinal and psychiatric disorders. The discussion emphasizes the importance of distinguishing MALS from other similar conditions, advocating for a thorough differential diagnosis process. A multidisciplinary approach to diagnosis and management is highlighted as essential for optimizing patient outcomes.