Most of us had only dealt with the pandemic in books or through the stories of grandparents or parents about the H1N1 flu pandemic that devastated the world between 1918 and 1920. That was only until 2019 expired, when the entire scientific community, and not only the medical and health one, has discovered that it was not prepared to face an emergency of this magnitude. Only the reorganization of the management of health, infrastructural and economic resources has made it possible to overcome this gap. The data for this study have been extracted from the hospital discharge registers of the Department of Urology of the A.O.U. “Federico II” in Naples, Italy. This work was preceded by other studies in which hospitalization procedures were compared between the Urology Department of the A.O.R.N. “Antonio Cardarelli” of Naples and the patients of the “San Giovanni di Dio e Ruggi d’Aragona” University Hospital in Salerno, Italy. In that case, too, data extraction was performed from the discharge registers of both hospitals. The experimental analysis was based on the comparison of the data relating to the year 2019 with those collected during the year 2020, burdened by the outbreak of the pandemic. The result has been a decrease in the number of pre-hospitalizations and an increase of planned hospitalizations, with a growth in the length of stay (LOS).