This study aims to investigate the impact of fire-retardant materials on delaying the flashover in the case of an airplane cargo compartment fire and highlights the proposal of using fire-retardant sheets in the cargo shipping field. The aircraft cargo compartment fire simulation is a theoretical scenario based on a previously validated model [10]. The models used in this study were based on the new version of the FDS program, which was previously validated [4]. The model employs large eddy simulations (LES) for turbulence and the eddy dissipation concept (EDC) as a combustion model, along with other models for thermal radiation, pyrolysis, and soot formation. The study yelled that the flashover will be delayed by a considerable amount of time compared to when the shipment materials are not protected, making this proposed study promising and valuable when it comes to the protection against fires in airplanes.