Multilateral relations between the European Union (EU) and Latin American and the Caribbean (LAC) countries have been dynamic spaces of economic, political, and social projects and practices at the interregional and global levels. This chapter discusses the effects of EU-LAC multilateralism on the (new) global order, exploring their institutionalized interregional cooperation as well as the patterns of convergence and divergence of their positions at the multilateral level for the cases of international security conflicts in Ukraine and Israel/Palestine.