Galls result from the abnormal growth of plant tissues triggered by the stimulus of different taxa of gall-inducing organisms. The gall tissues and gall-inducing organisms utilize primary metabolites for their respective needs: cell machinery maintenance and feed. The main primary metabolites commonly detected in galls include lipids, proteins, reducing sugars, and starch grains. These components are localized within different compartments of the gall tissues. Thus, we made a systematic review to bring the main aspects of primary metabolites in galls, highlighting the main storage sites, gall tissue compartments, and the relation of gall-inducer taxa with the metabolite compartmentalization. We confirm the morphofunctional compartmentalization of primary metabolites in gall tissues is associated with the taxa of gall-inducer organisms. Herein, we reinforce the significance of the gall-inducing organism in manipulating the metabolism of the host plant. This manipulation results in the formation of a gall with specific tissue organization that facilitates the gall-inducing feeding.