This chapter examines how 3D printing, robots, and the Internet of Things (IoT) have transformed medical production. It emphasizes the strict quality, precision, and safety criteria in medical manufacturing. The integration of intelligent and sustainable manufacturing technologies, notably 3D printing, might revolutionize medical device and implant production with improved accuracy, waste reduction, and inventory reduction. Robotics and automation improve efficiency, accuracy, and productivity while letting doctors concentrate on vital duties. Medical manufacturing uses smart sensors and IoT for real-time production monitoring and quality control. Intelligent and sustainable manufacturing, such as biodegradable materials and renewable energy, makes medical product manufacture more environmentally friendly. Medical production is transformed by 3D printing, which allows for specialized prostheses, surgical instruments, and implants. However, economic, material, and regulatory problems must be addressed. IoT applications in medical manufacturing include equipment monitoring, supply chain management, and patient monitoring. Benefits include better productivity, product quality, and safety; however implementation costs, cybersecurity risks, and data management complexity are noted. The chapter concludes by predicting the effects of sophisticated 3D printing, artificial intelligence, augmented and virtual reality, and the Internet of Medical Things on medical manufacturing. Also, the chapter discusses regulatory, cost, cybersecurity, and workforce development issues and solutions, encouraging the sector to collaborate, innovate, and invest to maximize these technologies’ patient outcomes and healthcare quality benefits.