Currently, there are no data on the frequency and prevalence, and we could not find a single scientific publication devoted to studying various aspects of fatty liver degeneration in patients with cardiovascular diseases in Kyrgyzstan. Cardiovascular disease and fatty liver disease are two serious and common medical conditions that significantly affect human health. The research aims to analyze the prevalence of fatty hepatosis among patients with cardiac diseases in the Southern Region of the Kyrgyz Republic at the Cardio Asia and Euroclinic medical clinics from 2019 to 2022. The research subjects are 3235 medical records of patients with diseases of the cardiovascular system. The authors conducted a descriptive-analytical study and carried out a statistical analysis of the time series of data from patients with fatty hepatosis. Quantitative, age, and gender indicators of patients with fatty hepatosis and cardiovascular diseases were calculated. The research showed that there was a decrease of 60.3% in 2020, and the rate of decline was 39.7%. In 2021, the decrease was 62.8%, the rate of decline was 37.2%. In 2022, there was an increase of 205.1%, with a growth rate of 105.1%. It is complicated to determine the actual indicators and frequency of the progress of the disease due to the lack of sensitive and specific screening techniques for detecting the initial, latent form of illness.