To achieve the goals of sustainable development [1], especially “Life Below the Water”, we have developed an innovative study exploring how to raise public awareness of Ocean Plastic Pollution by using Virtual Reality (VR). And we developed a VR project for the CAVE*™ Virtual Environment [2]. By utilizing the interactive experience with VR technology, our main goal is to show the public the huge damage of plastic pollution on whales and the ocean ecosystem. The reason why we designed this game was to allow players to experience the serious consequences of plastic pollution in person and to show some positive changes after successfully cleaning up the ocean. Our Virtual Reality experience emphasizes a practical solution by using “Aspergillus tubingensis” [3], a plastic-degrading fungus. After playing the game, players not only realize a deep understanding of the bad influence of plastic pollution in the ocean but also see the effectiveness of our solutions for reducing plastics. So that we can pay more attention to Sustainable Development Goals.