Dieulafoy lesions account for less than 5% of upper GI bleeds, but they can lead to significant morbidity and mortality. The lesions can be found throughout the GI tract; however, the majority of them are found in the stomach. Dieulafoy lesions are more common in men and in patients with other comorbidities such as chronic kidney disease and cardiovascular disease. Often repeated endoscopic evaluation is needed for identification of the lesion. If endoscopic evaluation fails to localize the lesion, capsule endoscopy or angiography can be utilized. Most Dieulafoy lesions can be controlled endoscopically or with coil angioembolization. Surgical intervention is reserved for lesions refractory to above measures.