The chapter “Considering Emerging Complementary and Alternative Treatments“delves into the diverse landscape of non-mainstream interventions for autism spectrum disorder (ASD). The discourse navigates through the historical evolution, current status, and future prospects of complementary and alternative medicine treatments. The narrative acknowledges the dichotomy between scientifically validated practices and those emerging from anecdotal and preliminary evidence. Key topics include vitamin and mineral supplementation, dietary interventions, secretin administration, chelation therapy, neurofeedback, sensory-based therapies, and facilitated communication. Each treatment is critically evaluated for its empirical support, safety, and clinical utility. The chapter emphasizes the necessity for rigorous research methodologies and balanced clinical perspectives in assessing these interventions. By providing a comprehensive overview, it aims to inform clinicians, researchers, and caregivers about the potential benefits and pitfalls of CAM treatments, fostering informed decision making in the therapeutic management of ASD.