Fertilizer is a key source of nutrients in agricultural land. Fertilizers can enhance nutrient availability in soil, which is directly related to plant growth and crop yield. To raise fertilizer quality, nanotechnology is emerging as a compelling prospective replacement for fertilizers. Nano-fertilizers refer to the fertilizers in nanosize from 1 to 100 nm sizes. Due to the large surface area-to-volume ratio, slow release of nutrients, high mobility, and solubility, nano-fertilizers are more efficient in less quantity than conventional fertilizers. Nano-formulation of any fertilizers enhances the crop yield by decreasing soil toxicity, possible side effects of overuse of synthetic fertilizers and enhancing nutritional use than conventional fertilizers. Nano-fertilizers are classified based on their action, nutrition and applied quantity. Nanomaterials act as carriers of nutrients in different ways, such as encapsulation of fertilizers in nanoparticles, nanoparticles that contain different nutrients, and synthesis of conventional fertilizers in their nanoforms. Nutrient-loaded nanosize materials, such as zeolite, chitosan, apatite and clay, some metal nanoparticles, and carbon nanoparticles are used as carriers of fertilizer. In this chapter, we have focused on the various carriers that are used in the formation and delivery of nanoscale fertilizers.