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Panel 33. A syncytium is a cell formed by the fusion of several cells that share their cytoplasm, but retain their individualized nuclei. The result is a giant cell with multiple nuclei, i.e. a “multi-nucleated” cell. This mechanism exists physiologically to generate multi-nucleated cells of the placenta, bone marrow, or muscle fiber. In the case of HIV, this phenomenon is pathological.

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HIV induced syncytium

  • 章节

  • 发表日期：

    2025年

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  • Philippe Roingeard

摘要

Panel 33. A syncytium is a cell formed by the fusion of several cells that share their cytoplasm, but retain their individualized nuclei. The result is a giant cell with multiple nuclei, i.e. a “multi-nucleated” cell. This mechanism exists physiologically to generate multi-nucleated cells of the placenta, bone marrow, or muscle fiber. In the case of HIV, this phenomenon is pathological.