Innovation is crucial for staying competitive in dynamic business environments, yet companies often face barriers that obstruct or delay innovation efforts. Despite extensive research over the past three decades, studies on solutions to these barriers are limited and there is a lack of a comprehensive analysis from a holistic perspective. This chapter addresses this research gap by summarizing current research and providing an overview of innovation barriers based on the External Environment and Organization Group Individual Barrier Model. The model examines both internal dimensions, such as organizational and individual factors, and external dimensions, including technological trends, market dynamics, and regulations. A case study of the German software provider DATEV eG explores approaches to overcome these barriers, such as orienting innovation fields, creating a transparent innovation portfolio, and implementing an intrapreneurship program. This study contributes to both academic and practical discussions on enhancing innovation by providing practical insights into overcoming innovation challenges.