This chapter highlights Jatropha biofuel crop climate change mitigation. The chapter starts with climate change and fossil fuels’ influence on global warming and lousy weather. This option enables biofuels to be studied as a greener, more sustainable energy source. Jatropha is a viable biofuel crop due to its oil output. Poor nations may create an eco-friendly energy source on non-arable land. Farmers and smallholders may exploit the plant's propensity to thrive in arid and semiarid conditions, including damaged and abandoned areas, to replace fossil fuels. Climate change causes droughts and rising seas in Bangladesh. Ideal for drought and salt, jatropha flourishes. Osmotic adjustment helps it thrive in water/salt-stressed soils, which may help climate-affected populations. Energy crops are investigated for climate change mitigation. Carbon sequestration from jatropha farming and renewable energy reduce climate change. Jatropha biodiesel may cut aviation and transportation greenhouse gas emissions. Agricultural resilience, carbon sequestration, and energy potential are highlighted. The chapter suggests Jatropha-based renewable energy to tackle the global energy and environmental crises.