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Limb amputations profoundly impact a person’s quality of life, necessitating advanced prosthetic solutions to overcome what otherwise become life-long disabilities. Despite robotic advancements, seamlessly integrating artificial limbs for intuitive control and sensory feedback remains challenging. Intuitive motor control and sensory feedback are crucial for prosthetic functionality. Techniques like Targeted Muscle Reinnervation (TMR) and Targeted Sensory Reinnervation (TSR) offer promising solutions by using reinnervated muscles and skin to mimic natural limb functions. Emerging methods such as Regenerative Peripheral Nerve Interfaces (RPNIs), Vascularized Denervated Muscle Targets (VDMTs), and Cutaneous Mechanoneural Interfaces (CMIs) face clinical implementation challenges due to their reliance on implanted electrodes. TMR and TSR enable non-invasive interfacing, but limitations in motor signal production and reinnervation maps persist. Innovative solutions for kinesthetic feedback and natural touch experiences are still under development. Ultimately, trade-offs between surgical and engineering approaches must be managed to achieve functional, user-friendly prosthetics suitable for daily life.

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Surgical Advancements to Enable the Integration of Bionic Limbs

  • 会议论文

  • 发表日期：

    2025年

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  • Max Ortiz-Catalan

摘要

Limb amputations profoundly impact a person’s quality of life, necessitating advanced prosthetic solutions to overcome what otherwise become life-long disabilities. Despite robotic advancements, seamlessly integrating artificial limbs for intuitive control and sensory feedback remains challenging. Intuitive motor control and sensory feedback are crucial for prosthetic functionality. Techniques like Targeted Muscle Reinnervation (TMR) and Targeted Sensory Reinnervation (TSR) offer promising solutions by using reinnervated muscles and skin to mimic natural limb functions. Emerging methods such as Regenerative Peripheral Nerve Interfaces (RPNIs), Vascularized Denervated Muscle Targets (VDMTs), and Cutaneous Mechanoneural Interfaces (CMIs) face clinical implementation challenges due to their reliance on implanted electrodes. TMR and TSR enable non-invasive interfacing, but limitations in motor signal production and reinnervation maps persist. Innovative solutions for kinesthetic feedback and natural touch experiences are still under development. Ultimately, trade-offs between surgical and engineering approaches must be managed to achieve functional, user-friendly prosthetics suitable for daily life.