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Squamous cell carcinoma (SCC) is the most common form of oral and head and neck cancer, accounting for more than 90% of cases diagnosed. SCC arises directly from the surface dysplastic mucosal epithelium and has a high propensity for cervical metastasis, and its prognosis has not improved over the past decades. In this chapter, key features of clinical presentation and histopathological features of SCC are discussed, with emphasis on those features that have a prognostic impact. Important variants of SCC and their diagnostic criteria are also discussed.

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Histopathology of Malignant Neoplasms of the Oral Mucosa-1

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  • 发表日期：

    2025年

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  • Benedict Seo

摘要

Squamous cell carcinoma (SCC) is the most common form of oral and head and neck cancer, accounting for more than 90% of cases diagnosed. SCC arises directly from the surface dysplastic mucosal epithelium and has a high propensity for cervical metastasis, and its prognosis has not improved over the past decades. In this chapter, key features of clinical presentation and histopathological features of SCC are discussed, with emphasis on those features that have a prognostic impact. Important variants of SCC and their diagnostic criteria are also discussed.