Flow control ventilation is an innovative technique of mechanical ventilation with a potentially lung protective characteristics. The constant inspiratory and expiratory flow, no ventilation pauses, and inspiration to expiration ratio 1:1 stand behind the idea of minimalization of dissipated energy in the lung. What is more, precise intratracheal pressure measurements enable deep insight into the respiratory mechanics. Preclinical data show attenuated lung injury, increased lung aeration, oxygenation, and gas exchange when flow control ventilation is applied to artificially injured porcine lung compared to conventional modes. The feasibility and safety of flow control ventilation in acute respiratory distress syndrome in humans is proven in a small number of trials. Some authors highlight the necessity to individualize ventilation to enhance possible benefits by identifying optimal positive end expiratory pressure and peak inspiratory pressure. The position of this ventilation mode in managing acute respiratory distress syndrome remains to be seen as more reliable data will be presented in literature. Possible shortcomings of this method can mention: limited data of ventilatory mechanics, inability to wean from ventilator, need for deep sedation, increased workload, and the issue of excessive airways secretions. There are several alternative uses for flow control ventilation and armamentarium of thin endotracheal tubes. Among others recently proposed novel technique of percutaneous tracheostomy with airways sealed with cuff of thin endotracheal tube downwards from the created stoma can be named. Such technique enables constant flow control ventilation and may possibly decrease the generation of aerosols.

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Flow Control Ventilation in Intensive Care Unit: ARDS, COVID, and Alternative Uses

  • Piotr Palaczynski,
  • Denis Kowalski,
  • Szymon Bialka

摘要

Flow control ventilation is an innovative technique of mechanical ventilation with a potentially lung protective characteristics. The constant inspiratory and expiratory flow, no ventilation pauses, and inspiration to expiration ratio 1:1 stand behind the idea of minimalization of dissipated energy in the lung. What is more, precise intratracheal pressure measurements enable deep insight into the respiratory mechanics. Preclinical data show attenuated lung injury, increased lung aeration, oxygenation, and gas exchange when flow control ventilation is applied to artificially injured porcine lung compared to conventional modes. The feasibility and safety of flow control ventilation in acute respiratory distress syndrome in humans is proven in a small number of trials. Some authors highlight the necessity to individualize ventilation to enhance possible benefits by identifying optimal positive end expiratory pressure and peak inspiratory pressure. The position of this ventilation mode in managing acute respiratory distress syndrome remains to be seen as more reliable data will be presented in literature. Possible shortcomings of this method can mention: limited data of ventilatory mechanics, inability to wean from ventilator, need for deep sedation, increased workload, and the issue of excessive airways secretions. There are several alternative uses for flow control ventilation and armamentarium of thin endotracheal tubes. Among others recently proposed novel technique of percutaneous tracheostomy with airways sealed with cuff of thin endotracheal tube downwards from the created stoma can be named. Such technique enables constant flow control ventilation and may possibly decrease the generation of aerosols.