Sinonasal malignant tumors are rare, accounting for less than 1% of all malignancies and approximately 3–5% of head and neck malignancies. The most common type is squamous cell carcinoma, followed by adenocarcinoma. Other less common types are adenoid cystic carcinoma, esthesioneuroblastoma, mucosal malignant melanoma, and undifferentiated carcinoma. Common symptoms of sinonasal malignancy include nasal obstruction, episodes of epistaxis, recurrent sinusitis, sinus pain, otalgia, rhinorrhea, tearing from one nostril, loss of smell, and facial swelling. Other symptoms such as an asymptomatic neck mass, facial paresthesia, cranial nerve palsy (paralysis), proptosis, diplopia - visual disturbances, loosening of teeth, and trismus may indicate advanced disease. The clinical diagnostic process includes anterior rhinoscopy, nasendoscopy, examination of the oral cavity, neck palpation, cranial nerve examination, and ophthalmologic examination. MRI scan and CT scan are the preferred imaging tools for assessing and planning surgical treatment for malignant sinonasal tumors. Intestinal type adenocarcinoma of the paranasal sinuses is considered an occupational disease, particularly affecting workers exposed to wood or leather dust. Smoking is also associated with sinonasal malignancies. Adenocarcinoma typically arises from the ethmoid sinuses, in contrast to SCC, which usually arises from the maxillary sinuses. Most sinonasal malignant tumors are treated surgically. For patients with advanced disease, a multimodality treatment approach including surgery and chemoradiotherapy should be considered.

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Sinonasal Malignancy

  • Konstantinos Geronatsios

摘要

Sinonasal malignant tumors are rare, accounting for less than 1% of all malignancies and approximately 3–5% of head and neck malignancies. The most common type is squamous cell carcinoma, followed by adenocarcinoma. Other less common types are adenoid cystic carcinoma, esthesioneuroblastoma, mucosal malignant melanoma, and undifferentiated carcinoma. Common symptoms of sinonasal malignancy include nasal obstruction, episodes of epistaxis, recurrent sinusitis, sinus pain, otalgia, rhinorrhea, tearing from one nostril, loss of smell, and facial swelling. Other symptoms such as an asymptomatic neck mass, facial paresthesia, cranial nerve palsy (paralysis), proptosis, diplopia - visual disturbances, loosening of teeth, and trismus may indicate advanced disease. The clinical diagnostic process includes anterior rhinoscopy, nasendoscopy, examination of the oral cavity, neck palpation, cranial nerve examination, and ophthalmologic examination. MRI scan and CT scan are the preferred imaging tools for assessing and planning surgical treatment for malignant sinonasal tumors. Intestinal type adenocarcinoma of the paranasal sinuses is considered an occupational disease, particularly affecting workers exposed to wood or leather dust. Smoking is also associated with sinonasal malignancies. Adenocarcinoma typically arises from the ethmoid sinuses, in contrast to SCC, which usually arises from the maxillary sinuses. Most sinonasal malignant tumors are treated surgically. For patients with advanced disease, a multimodality treatment approach including surgery and chemoradiotherapy should be considered.