The speed at which digital technologies develop creates a demand to continually embrace new work tools and digitalized work processes. The current chapter acknowledges this expectation and makes a case for how people’s digital mindset, a set of generalized beliefs about personal and situational resources in the context of technological change, can influence their engagement with new digital technologies at work. In this chapter, we introduce the digital mindset concept and the fixed and growth beliefs about personal resources and zero-sum and expandable-sum beliefs about situational resources that comprise it. We describe the influence that these different beliefs can have on a person’s perceptions of, reactions to, and efforts to use new digital technologies at work. We also present a framework for how these beliefs may interact in shaping responses. We then describe findings from two empirical studies, focussed on how digital mindset relates to (1) feelings of helplessness in virtual teams and (2) manager’s provision of development support to their employees. In the final section, we provide practical recommendations and present techniques aiming to assess and develop one’s digital mindset.