Ejaculatory dysfunction is a term that describes a spectrum of debilitating diseases that impacts the quality of life of men affected. This spectrum comprises a range of symptoms and the most common subtypes encountered can be summarized as premature ejaculation (PE), delayed ejaculation (DE), anejaculation, retrograde ejaculation (RE), painful ejaculation, post-orgasmic illness syndrome (POIS), and many others. Diagnosis is challenging considering patient hesitancy for medical care seeking, high variety in presenting symptoms, and lack of consensus in diagnosing criteria. There are many treatment modalities that target each subtype of the spectrum and can broadly be categorized into psychological therapy, pharmacologic treatment, local therapies, surgical treatments, and combinations of these. In this chapter, we aim to provide background and review the current and emerging treatment modalities for each subtype of ejaculatory dysfunction.