Stimulated emission is the physical principle of laser beam generation. Laser energy varies according to its wavelength. There are several types of ophthalmic lasers that can produce thermal, chemical, or mechanical effects on the ocular tissues. Several factors determine the impact of a laser, such as the degree of absorption of tissue pigments of a specific laser wavelength, laser power, the size of the laser spot on the target tissue, the duration of application, and media clarity. Laser delivery systems can be attached to slit lamp and indirect ophthalmoscope, or laser can be delivered through a fiber-optic probe. Advanced delivery systems enabled for more tolerable, precise, and shorter treatment sessions. Techniques of ophthalmic laser therapy include laser photocoagulation, transpupillary thermotherapy, and photodynamic therapy. These laser techniques are used in ophthalmic oncology as a primary or adjuvant tumor treatment and as a treatment for some radiation-induced toxicities.