As new technologies and ways of working emerge, there does not always require completely new ways of doing things. Sometimes, adapting to changes requires reanalyzing the old ways of doing things to see how these effective methods can be applied in new situations or in this case new VR environments. VR work environments require different structures and skills than traditional work environments. There are best practices and strategies that have been effective for learning and career development in traditional environments that have been adapted in this chapter to meet the needs of VR employees. The skills development strategies and factors of relationship building, networking, effective communication, skill development techniques, personal branding, ethics, and understanding of organizational culture when aligned with accumulation of information, change in behavior, improved performance, change in knowledge, attitudes, and skills, a new sense of meaning, cognitive restructuring, and personal transformation all contribute to successful VR career development of employees when supported by organization leaders.