In the present work, finite element modeling of the uniaxial compression process of polymer scaffolds with increasing wall thickness values was carried out. The method for using X-ray computed microtomography to construct the finite element model was proposed, and evolution of the deformation process of internal structure of the scaffolds was studied. The mechanical characteristics of the polymer material used in printing of the scaffolds were evaluated using nanoindentation. The results obtained may be useful for optimizing the design of scaffolds and increasing their efficacy in regenerative medicine applications.

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Finite Element Modeling of Uniaxial Compression of Scaffolds

  • Roman V. Karotkiyan,
  • Evgeniy V. Sadyrin,
  • Andrey L. Nikolaev,
  • Sergei V. Chapek,
  • Andrey S. Vasiliev

摘要

In the present work, finite element modeling of the uniaxial compression process of polymer scaffolds with increasing wall thickness values was carried out. The method for using X-ray computed microtomography to construct the finite element model was proposed, and evolution of the deformation process of internal structure of the scaffolds was studied. The mechanical characteristics of the polymer material used in printing of the scaffolds were evaluated using nanoindentation. The results obtained may be useful for optimizing the design of scaffolds and increasing their efficacy in regenerative medicine applications.