This chapter delves into the complex ethical landscape that underpins the deployment of AI in Middle Eastern businesses. It grapples with the dilemmas surrounding the influence of AI, on matters concerning privacy, job opportunities, and fairness. The discourse extends to how AI could potentially exacerbate or mitigate social and economic disparities. The chapter also examines the frameworks being developed to ensure ethical AI use, discussing the role of collaborations and local governance in upholding ethical standards. Furthermore, it explores the balance between innovation and ethical considerations, highlighting the voices of local experts, business leaders, and ethicists who are shaping the responsible use of AI in the Middle East.