Despite global efforts to achieve the UN Agenda 2030 and the Sustainable Development Goals (SDGs), progress remains insufficient. Embracing the concept of eudaimonia, which prioritizes practical wisdom and excellence as core to human well-being, is deemed essential to achieve the significant transformations necessary for a sustainable future for people and the planet. Based on this assumption, a framework for enhancing public administration systems (PAS) guided by the principles of eudaimonia is developed throughout this chapter. Overall, the framework aims to clarify how the administrative direction, organization, and skills in public administration systems can be built on a foundation of core eudaimonic values such as equity, innovation and stewardship. Based on this analysis, the chapter sketches a viable transformation agenda for making PAS develop in the intended direction in order to become much more responsive to the imperative for immediate action and to develop innovative strategies to drive sustainable development. By designing PAS based on principles of eudaimonia, a future is envisioned where such systems are able to steward the needed societal transformation at the speed and magnitude required to address the multifaceted challenges of the twenty-first century.