The nasal septum comprises septal cartilage, ethmoid bone, and vomer. It sits on the premaxilla and maxillary crest. Its arterial blood supply comes from branches of the internal and external carotid arteries. These branches are the anterior and posterior ethmoidal arteries and the sphenopalatine artery. Kiesselbach’s plexus is the most common area for epistaxis and is formed by the anterior and posterior ethmoidal arteries, the superior labial artery, the greater palatine artery, and the posterior septal branch of the sphenopalatine artery. The veins of the nasal cavity accompany the arteries and have the same names. They drain into the facial vein, the pterygoid plexus, and the cavernous sinus. The nasal cavity is innervated by the olfactory, ophthalmic, and maxillary nerves. The nasociliary nerve originates from the ophthalmic nerve and gives rise to the posterior and anterior ethmoid nerves. The pterygopalatine ganglion is created by the maxillary nerve and gives rise to the nasopalatine nerve, the posterior superior lateral nasal nerve, the posterior inferior lateral nasal nerve, the greater palatine nerve, the lesser palatine nerve, and the pharyngeal nerve.