An MPC control strategy activated by events is developed, where the event determines when to perform the control calculation and, therefore, when to apply insulin to the person with type 1 diabetes. The system’s emulation environment uses the hardware-in-the-loop methodology to evaluate not only the new strategy’s performance in glycemic regulation but also the use of limited hardware resources based on a Raspberry Pi3B embedded system integrated with a battery manager and an experimental ultra-low-cost insulin infuser. The results show that the control strategy that integrates event triggering achieves regulation of test patients despite facing emulation scenarios with measurement noise, parametric variations, and without food announcements with a similar performance to the standard time-triggered strategy. The strategy permits increasing the device’s operating time up to three times compared to the controller activated in each sampling period.