Nail toxicity is an underrecognized side effect associated with chemotherapy [1, 2]. The cytotoxic effects of antineoplastic medications, particularly those with antimitotic activity, are thought to disrupt the normal growth of nail matrix cells, triggering nail changes [2, 3]. As a result, nail toxicities commonly involve multiple nails and occur in conjunction with drug administration [4].

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Nail Dystrophies Secondary to Chemotherapies

  • Eden Axler,
  • Shari R. Lipner

摘要

Nail toxicity is an underrecognized side effect associated with chemotherapy [1, 2]. The cytotoxic effects of antineoplastic medications, particularly those with antimitotic activity, are thought to disrupt the normal growth of nail matrix cells, triggering nail changes [2, 3]. As a result, nail toxicities commonly involve multiple nails and occur in conjunction with drug administration [4].