Climate Change has threatened human development in many ways. Threats to global food production are among the critical issues faced by development planners, where agro-ecosystems resilience has become one of the concerned topics under sustainable development. Therefore, it is important to develop, update, and disseminate knowledge related to agro-ecosystem resilience for future food security. In that context, higher education institutes are capable of promoting agro-ecosystems resilience. This research is conducted as a partial requirement of the Building Resilience in Tropical Agro-Ecosystems (BRITAE) project co-funded by the Erasmus + Programme of the European Union. The objective of this research is to evaluate the involvement of higher education institutions when promoting agro-ecosystems resilience. This research was based on a literature review where systematic and snowball methods were combined. The systematic literature review was conducted based on three academic databases of Scopus, science direct, and emerald. There were 88 research papers selected for the thematic analysis. Results have shown that the higher education institutions act as the mechanism of integration between all stakeholders where individual farmers, policymakers, research institutions, and industries are connected. However, lack of financial assistance and lack of cutting-edge facilities are some of the challenges faced by higher education institutes. Results have also pointed out that sustainable management, entrepreneurship, policies, resilience mechanisms, climate change, and productivity management are key areas to be improved in the higher education sector when promoting agro-ecosystem-based resilience. Higher education institutions being one of the contributors towards agro-ecosystems resilience have been actively involved in promoting resilience. Nevertheless, with the improvement of the areas mentioned above, it can contribute even more toward global food security and ecosystems resilience.