To achieve interactive in situ visualization in immersive virtual environments, the parallel visualization tool Vistle has been coupled with the SENSEI in situ framework. Vistle’s modular architecture, designed for distributed systems, allows in situ, hybrid and in transit workflows. A key feature is the ability to interactively configure the visualization pipeline during simulation runtime, even from within 3D virtual environments. Therefore, Vistle’s in situ analysis runs concurrently with the simulation to apply user input to the visualization of the current simulation iteration. The trade-off is additional memory consumption. Initial benchmarks on small-scale simulations show promising results in terms of total runtime overhead, provided the visualization pipeline has enough CPU resources to complete before the next visualization iteration is triggered. For interactive in situ visualizations, remote rendering of large data objects combined with in transit visualization of smaller ones has proven to be the most effective.