In the following paper the numerical analysis of thermal process occurring in biological tissue when exposed to laser irradiation is presented. The heat transfer model is founded on the Pennes equation and it is assumed to be transient and one-dimensional. Additionally, the internal heat sources resulting from laser irradiation based on the Beer law are taken into account. Moreover, it treats perfusion rate and the effective scattering coefficient as variables dependent on tissue damage. For numerical calculations the Finite Pointset Method has been used. The paper concludes by presenting the obtained results. Then results are compared to existing literature findings to assess the accuracy of the computations.