Mixed Reality systems aim to estimate a user’s full-body joint configurations from just the pose of the end effectors, primarily head and hand poses. Existing methods often involve solving inverse kinematics (IK) to obtain the full skeleton from just these sparse observations, usually directly optimizing the joint angle parameters of a human skeleton. Since this accumulates error through the kinematic tree, predicted end effector poses fail to align with the provided input pose. This leads to discrepancies between the predicted and the actual hand positions or feet that penetrate the ground. In this paper, we first refine the commonly used SMPL parametric model by embedding anatomical constraints that reduce the degrees of freedom for specific parameters to more closely mirror human biomechanics. This ensures that our model produces physically plausible pose predictions. We then propose a biomechanically accurate neural inverse kinematics solver (MANIKIN) for full-body motion tracking. MANIKIN is based on swivel angle prediction and perfectly matches input poses while avoiding ground penetration. We evaluate MANIKIN in extensive experiments on motion capture datasets and demonstrate that our method surpasses the state of the art in quantitative and qualitative results at fast inference speed.