Due to the reasons of complexity and uncertainty in the construction of high-rise buildings, the problem of safety risk in the construction process is particularly prominent. For this reason, this paper is based on the entropy right method, combined with the characteristics from the high-rise building construction, the four key factors of personnel risk, material risk, environmental risk and management risk are screened and analysed. The safety risk assessment system for high-rise building construction based on computer BIM technology can intelligently recognise the safety risks in high-rise building implementation and weight the various safety administration indexes in the process of high-rise building construction, which improves the scientificity of the weight setting. The safety risk evaluation level of computer BIM technology in high-rise building construction was determined, and the entropy weighting method was used to evaluate the safety risk of computer BIM technology. The findings show as follows, the weights of the first-level indicators are in descending order: personnel risk (0.3338) > material risk (0.2585) > environmental risk (0.2391) > management risk (0.1756); and among the 12 s-level indicators, the three indicators with the highest weights are compliant construction C1, safety protection facilities C5, and safety technology management C11.Therefore, it is necessary to have targeted improve the safety technology of risk source analysis in the construction of tall buildings and apply new information technology, such as BIM, to the safety risk management of tall building works in such a way as to make certain that the construction unit finds the dangers in a timely manner and takes measures towards the improvement of the management of the basic security construction technology. Moreover, it can provide theoretical basis and guidance for the future safety risk assessment of high-rise building structures based on computerised BIM technology.