This paper investigates the role of digital twins in line manufacturing equipment implementation and change processes, addressing gaps in academic research on success and failure. Focusing on Industry 4.0, the study explores whether digital twins are sufficient or additional perspectives are needed for improving the implementation. It identifies challenges in contemporary academic investigations and emphasizes the scope of implementation issues, including quality, capability risks, and infrastructural elements. The paper presents cases from diverse industries, revealing challenges in the implementation process despite virtual commissioning. This indicates contrasting views related to the limitations of digital twins. The findings highlight the need for a more holistic research approach considering human, infrastructural, and operational elements in line manufacturing implementation. A proposed research agenda aims to enhance understanding and effectiveness in implementing production line equipment, emphasizing a balanced view hybridizing technological and economic, operational, and organizational factors for a first-time-right implementation thinking.