The concept of othering describes the processes through which individuals or groups are categorized as “others,” based on social characteristics such as their origin, gender, class or age. Inscribed in asymmetrical social relationships, these processes reinforce relationships of domination while, at the same time, they produce identitary effects on otherized people as well as on those defining the norm. This entry explores othering processes in the field of health and caregiving, particularly regarding mental health, starting from a revision of the anthropological and sociological literature. We show that othering is an ambivalent process: It can generate stigmatization and exclusion, as well as resistances and negotiations. The complex ties between othering and empathy illustrate this ambivalence. These dynamics depend on the specific social conditions in which they are established, in two indisociable levels: in care-related interactions and the institutional, political and sociohistorical frames that shapes them. Age constitutes a still understudied but central dimension in the construction of forms of alterity: Its analysis opens new tracks for research.