This chapter introduces two valuable tools widely utilized in computational biology: GitHub and Jupyter Notebooks. GitHub provides a robust environment for managing project data, offering features for backup, dissemination, and collaboration. You can organize your projects within folders and files, selecting specific items for backup, and a versioned history of your project. This versioning system allows for easy rollback to earlier states, ensuring data integrity. Jupyter Notebooks, on the other hand, offer a flexible platform for combining programming code and documentation within a web browser interface. These notebooks facilitate collaboration by enabling easy exchange of files among collaborators, allowing recipients to execute all code contained within the notebook. This feature-rich environment enhances reproducibility and transparency in computational biology research by providing a unified platform for code execution and documentation.