Pre- and post-synaptic events are regulated by liquid–liquid phase separation and this phenomenon requires multiple electrical forces. Both axonal transport and the organization of postsynaptic excitatory and inhibitory receptors are regulated by LLPS, with its mandatory electrical drivers ultimately determining our cognitive health and capacity.

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Synaptic Physiology Depends on Electrical Forces and Liquid–Liquid Phase Separation

  • Colin D. McCaig

摘要

Pre- and post-synaptic events are regulated by liquid–liquid phase separation and this phenomenon requires multiple electrical forces. Both axonal transport and the organization of postsynaptic excitatory and inhibitory receptors are regulated by LLPS, with its mandatory electrical drivers ultimately determining our cognitive health and capacity.