This concluding chapter will summarize the progress that has already been made and reflect on the opportunities and ongoing needs for advancing the field of pediatric sedation. The future of pediatric sedation will benefit from our ability to more accurately target and achieve the optimal level of sedation, analgesia, and amnesia needed for a given procedure. Advances in sedation will require that we improve our ability to proactively identify, anticipate, prepare for, and treat adverse events. The important areas that remain to be explored and advanced will be reviewed.