Most of the reactive metals may be separated by a high-temperature operation in their solid chloride salt form. The efficiencies of the separation depend on the vapour pressures of the corresponding salts with alkali chlorides. It may be beneficial to explore the possibility of performing the separation at lower temperatures in a mixture of two or more solid solutions and in a liquid salt formed by mixing two alkali chloride salts of the refractory metals. In this work, thermodynamic calculations using the Flood, Forland, Grjotheim (FFG) molten salt cycles are presented pertaining to the separation of refractory metals using solid or liquid mixtures of alkali chlorides.